49ers vs Titans Week 16 2021: Final Score 20

Final2021 Week 16

Nissan Stadium, Nashville, TNThu, Dec 23, 2021, 8:20 PM ET

San Francisco 49ers vs Tennessee Titans, Week 16 2021

San Francisco 49ers

Away

Tennessee Titans

HomeWon

Scoring by quarter
Team	Q1	Q2	Q3	Q4	Final
49ers	7	3	0	7	17
Titans	0	0	10	10	20

SF 17TEN 20 Final

Passing leader
Jimmy Garoppolo
SF · QB
15.2PPR pts
26/35, 322 YDS, 1 TD, 2 INT
Top fantasy scorer
A.J. Brown
TEN · WR
31.5PPR pts
11 REC, 145 YDS, 1 TD
49ers leader
Deebo Samuel Sr.
SF · WR
28.1PPR pts
9 REC, 159 YDS
Defensive playmaker
Amani Hooker
TEN
1 INT, 6 TKL

Titans 20, 49ers 17: Tennessee rallies from 10 down at halftime

Tennessee erased a 10–0 halftime deficit, outscoring San Francisco 20–7 after the break to win 20–17. San Francisco outgained the Titans 389–278.

The 49ers went 3-for-8 on third down and committed two turnovers, while the Titans finished without a giveaway.

Key advantages

+2 turnover margin TEN 0 turnovers
+18% third-down rate TEN 56% · SF 38%

Game Highlights

Official NFL highlights · Opens from YouTube

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Why the Titans Won

Tennessee won the turnover and third-down battles.

Team stats comparison, 49ers vs Titans
49ers	Stat	Titans
2	Turnovers	0

38%	Third-down conversion	56%

Other team stats
389	Total yards	278

6.7	Yards per play	4.8

58	Plays	58

30:31	Time of possession	29:29

Scoring Summary

The Titans scored two touchdowns and two field goals; the 49ers scored two touchdowns and one field goal.

Scoring plays, 49ers vs Titans
Time	Team	Play	SF	TEN
1st quarter
9:57	SF	Jeff Wilson Jr. 1-yard TD run Takes leadRobbie Gould XP	7	0
2nd quarter
8:31	SF	Robbie Gould 48-yard FG Extends lead	10	0
3rd quarter
8:45	TEN	Randy Bullock 38-yard FG	10	3
7:13	TEN	D'Onta Foreman 3-yard TD run Ties gameRandy Bullock XP	10	10
4th quarter
13:02	TEN	Ryan Tannehill → A.J. Brown, 18-yard TD Takes leadRandy Bullock XP	10	17
2:20	SF	Jimmy Garoppolo → Brandon Aiyuk, 2-yard TD Ties gameRobbie Gould XP	17	17
0:04	TEN	Randy Bullock 44-yard FG Game winner	17	20

Fantasy Points: 49ers vs Titans, Week 16 2021

Fantasy leaders

A.J. BrownTENWR31.5 PTSWR3
Deebo SamuelSFWR26.1 PTSWR5
Jimmy GaroppoloSFQB15.2 PTSQB15
Jeff WilsonSFRB14.7 PTSRB16

Player Stats

Quarterbacks

Quarterback statistics
Player	FPTS	FIN	CMP/ATT	Pass YDS	TD	INT	Rush ATT	Rush YDS	Rush TD	Rate	Start/Sit
Jimmy GaroppoloSFQB	15.2	QB15	26/35	322	1	2	1	3	0	88.0
Ryan TannehillTENQB	14.6	QB16	22/29	209	1	0	3	22	0	106.8

WRs, RBs, & TEs

Receiver, running back and tight end statistics
Player	FPTS	FIN	POS	Rush ATT	Rush YDS	Rush TD	TGT	REC	Rec YDS	Rec TD	Start/Sit
A.J. BrownTENWR	31.5	WR3	WR	—	—	—	16	11	145	1
Deebo SamuelSFWR	26.1	WR5	WR	5	32	0	11	9	159	0
Jeff WilsonSFRB	14.7	RB16	RB	14	45	1	3	3	12	0
Brandon AiyukSFWR	14.0	WR28	WR	—	—	—	5	4	40	1
D'Onta ForemanTENRB	7.7	RB37	RB	9	17	1	—	—	—	—
Nick Westbrook-IkhineTENWR	5.8	WR71	WR	—	—	—	3	2	38	0	Start/Sit →
JaMycal HastySFRB	4.9	RB45	RB	1	3	0	3	3	26	0
George KittleSFTE	4.1	TE31	TE	—	—	—	3	2	21	0	Start/Sit →
Geoff SwaimTENTE	4.0	TE32	TE	—	—	—	3	3	10	0
Jauan JenningsSFWR	3.9	WR86	WR	—	—	—	5	2	19	0	Start/Sit →
Dontrell HilliardTENRB	3.4	RB58	RB	5	20	0	2	2	-6	0
Jeremy McNicholsTENRB	3.1	RB61	RB	7	31	0	1	0	0	0
Anthony FirkserTENTE	2.3	TE42	TE	—	—	—	1	1	13	0
Julio JonesTENWR	1.7	WR103	WR	—	—	—	1	1	7	0
Chester RogersTENWR	1.3	WR112	WR	—	—	—	1	1	3	0
Racey McMathTENWR	0.0	—	WR	—	—	—	1	0	0	0

Fantasy Usage

San Francisco 49ers

Snap Share

George KittleTE59 snaps100%
Brandon AiyukWR55 snaps93%
Deebo SamuelWR45 snaps76%
Jeff WilsonRB44 snaps75%
Jauan JenningsWR27 snaps46%

Target Share30 targets

Deebo Samuel37%, 11 targets
Brandon Aiyuk17%, 5 targets
Jauan Jennings17%, 5 targets
George Kittle10%, 3 targets
Jeff Wilson10%, 3 targets
Other10%, 3 targets

Carry Share21 carries

Jeff Wilson67%, 14 carries
Deebo Samuel24%, 5 carries
Jimmy Garoppolo5%, 1 carries
JaMycal Hasty5%, 1 carries

Tennessee Titans

Snap Share

A.J. BrownWR46 snaps74%
Geoff SwaimTE39 snaps63%
Nick Westbrook-IkhineWR39 snaps63%
Julio JonesWR31 snaps50%
Chester RogersWR31 snaps50%

Target Share29 targets

A.J. Brown55%, 16 targets
Geoff Swaim10%, 3 targets
Nick Westbrook-Ikhine10%, 3 targets
Dontrell Hilliard7%, 2 targets
Julio Jones3%, 1 targets
Other14%, 4 targets

Carry Share24 carries

D'Onta Foreman38%, 9 carries
Jeremy McNichols29%, 7 carries
Dontrell Hilliard21%, 5 carries
Ryan Tannehill13%, 3 carries

View full usage tableHide full usage table

Offensive snaps and share for the skill positions
Player	SNAPS	SNAP %	TGT	TGT %	CAR
George KittleSFTE	59	100%	3	10%	0
Brandon AiyukSFWR	55	93%	5	17%	0
Deebo SamuelSFWR	45	76%	11	37%	5
Jeff WilsonSFRB	44	75%	3	10%	14
A.J. BrownTENWR	46	74%	16	55%	0
Geoff SwaimTENTE	39	63%	3	10%	0
Nick Westbrook-IkhineTENWR	39	63%	3	10%	0
Julio JonesTENWR	31	50%	1	3%	0
Chester RogersTENWR	31	50%	1	3%	0
Jauan JenningsSFWR	27	46%	5	17%	0
MyCole PruittTENTE	27	44%	0	0%	0
Jeremy McNicholsTENRB	26	42%	1	3%	7
D'Onta ForemanTENRB	21	34%	0	0%	9
Anthony FirkserTENTE	16	26%	1	3%	0
Dontrell HilliardTENRB	13	21%	2	7%	5
Trent SherfieldSFWR	12	20%	0	0%	0
JaMycal HastySFRB	11	19%	3	10%	1
Racey McMathTENWR	10	16%	1	3%	0
Charlie WoernerSFTE	5	8%	0	0%	0
Travis BenjaminSFWR	4	7%	0	0%	0
Ross DwelleySFTE	1	2%	0	0%	0

Fantasy Points vs Expected

PPRHalf PPRStandard

Expected points (xFP) are what a player's pass attempts, carries and targets are worth at the league's average rates; the difference is what the player made of them.

Biggest overperformer+6.4Deebo Samuel Sr.28.1 PTS vs 21.7 xFP
Biggest underperformer−4.5Jauan Jennings3.9 PTS vs 8.4 xFP
Highest expected volume27.4 xFPA.J. Brown31.5 PTS scored

Usage and expected fantasy points
Player	PTS	xFP	vs xFP	Snap%	Usage	Rte%	Pass att	Car	Car%	Tgt	Tgt%
A.J. BrownTEN · WR	31.5	27.4	+4.1	74%	53% tgt	—	1	0	0%	16	53%
Deebo Samuel Sr.SF · WR	28.1	21.7	+6.4	76%	31% tgt	—	0	5	24%	11	31%
Jimmy GaroppoloSF · QB	15.2	16.0	−0.8	100%	35 att	—	35	1	5%	0	0%
Ryan TannehillTEN · QB	14.6	14.7	−0.1	100%	29 att	—	29	3	13%	0	0%
Jeff Wilson Jr.SF · RB	14.7	14.0	+0.7	75%	67% car	—	0	14	67%	3	9%
Brandon AiyukSF · WR	14.0	8.4	+5.6	93%	14% tgt	—	0	0	0%	5	14%
Jauan JenningsSF · WR	3.9	8.4	−4.5	46%	14% tgt	—	0	0	0%	5	14%
Kyle JuszczykSF · RB	7.5	8.4	−0.9	—	14% tgt	—	0	0	0%	5	14%
Dontrell HilliardTEN · RB	3.4	6.6	−3.2	21%	21% car	—	0	5	21%	2	7%
Jeremy McNicholsTEN · RB	3.1	6.2	−3.1	42%	29% car	—	0	7	29%	1	3%
D'Onta ForemanTEN · RB	7.7	5.8	+1.9	34%	38% car	—	0	9	38%	0	0%
JaMycal HastySF · RB	5.9	5.7	+0.2	19%	9% tgt	—	0	1	5%	3	9%
Geoff SwaimTEN · TE	4.0	5.1	−1.1	63%	10% tgt	—	0	0	0%	3	10%
George KittleSF · TE	4.1	5.1	−1.0	100%	9% tgt	—	0	0	0%	3	9%
Nick Westbrook-IkhineTEN · WR	5.8	5.1	+0.7	63%	10% tgt	—	0	0	0%	3	10%
Anthony FirkserTEN · TE	2.3	1.7	+0.6	26%	3% tgt	—	0	0	0%	1	3%
Chester RogersTEN · WR	1.3	1.7	−0.4	50%	3% tgt	—	0	0	0%	1	3%
Julio JonesTEN · WR	1.7	1.7	0.0	50%	3% tgt	—	0	0	0%	1	3%
Khari BlasingameTEN · RB	0.9	1.7	−0.8	—	3% tgt	—	0	0	0%	1	3%
Racey McMathTEN · WR	0.0	1.7	−1.7	16%	3% tgt	—	0	0	0%	1	3%

Team totals: 49ers 35 targets and 21 carries; Titans 30 targets and 24 carries. Shares are from the box score. Snap counts are from the weekly player logs (Sleeper), and include plays wiped out by penalties. Route counts, air yards and red-zone touches appear when the tracking feed is connected. League-average rates from the 2021 season: 1.68 PPR points per target (67% catch rate), 0.64 per carry and 0.44 per pass attempt. They don't adjust for field position or target depth.

Fantasy Verdicts

Jimmy Garoppolo

SF · QB · 15.2 pts on 16.0 expected

26 of 35 passing for 322 yards, 1 touchdown, 2 interceptions; 1 carry for 3 yards.

Verdict: The points matched the role, 16.0 expected.

Ryan Tannehill

TEN · QB · 14.6 pts on 14.7 expected

22 of 29 passing for 209 yards, 1 touchdown; 3 carries for 22 yards.

Verdict: The points matched the role, 14.7 expected.

No interceptions after 6 in the previous four games.

Deebo Samuel Sr. Ran hot

SF · WR · 28.1 pts on 21.7 expected

11 targets (31% of the team's), 9 catches for 159 yards; 5 carries (24% of the team's) for 32 yards.

Verdict: The opportunities were worth 21.7 points; efficiency supplied the rest.

Best score since Week 10. A touchdown in 5 of the last 8 games.

Jeff Wilson Jr. Strong role

SF · RB · 14.7 pts on 14.0 expected

3 targets (9% of the team's), 3 catches for 12 yards; 14 carries (67% of the team's) for 45 yards and 1 touchdown.

Verdict: The points matched the role, 14.0 expected.

A.J. Brown Strong role

TEN · WR · 31.5 pts on 27.4 expected

0 of 1 passing for 0 yards; 16 targets (53% of the team's), 11 catches for 145 yards and 1 touchdown.

Verdict: The points matched the role, 27.4 expected.

Season high in targets (16). Best score since Week 8.

Dontrell Hilliard

TEN · RB · 3.4 pts on 6.6 expected

2 targets (7% of the team's), 2 catches for -6 yards; 5 carries (21% of the team's) for 20 yards.

Verdict: The points matched the role, 6.6 expected.

Brandon Aiyuk Ran hot

SF · WR · 14.0 pts on 8.4 expected

5 targets (14% of the team's), 4 catches for 40 yards and 1 touchdown.

Verdict: The opportunities were worth 8.4 points; the touchdowns supplied the rest, and they are the part least likely to repeat.

Jauan Jennings

SF · WR · 3.9 pts on 8.4 expected

5 targets (14% of the team's), 2 catches for 19 yards.

Verdict: The points matched the role, 8.4 expected.

Start/Sit: Jauan Jennings →

Stock Up, Stock Down

San Francisco 49ers

Stock up: Jeff Wilson Jr. played 75% of the snaps, up from a 42% season average.
Stock up: Jauan Jennings played 46% of the snaps, up from a 28% season average.

Tennessee Titans

Stock up: Jeremy McNichols led the backfield with 42% of the snaps after trailing Dontrell Hilliard before this game.
Stock down: Dontrell Hilliard lost the backfield lead: 21% of the snaps to Jeremy McNichols's 42%.

Fantasy Matchups

Fantasy points allowed per game by position, 2021 through Week 18.

Fantasy points allowed per game by position, 49ers defense and Titans defense
Points allowed to	49ers D	Titans D
QBs	17.7	18.0
RBs	20.9	16.1
WRs	35.4	40.9
TEs	9.1	8.7

Regular season, summed from each game's box score and scored with this page's rules.

How the Game Swung

Tennessee opened at 40% win probability, fell as low as 9%, then rallied to win.

Titans win probability

Key Swings

−19Wilson 1-yd TD run40% → 21%Q1 9:57
+28Foreman 3-yd TD run16% → 44%Q3 7:13
+39Tannehill → Brown, 18-yd TD45% → 84%Q4 13:02
−52Garoppolo → Aiyuk, 2-yd TD>99% → 48%Q4 2:20
+50Bullock 44-yd FG50% → >99%Q4 0:04

Swing in Titans win probability, in points

Play Calling and Possessions

Play calling, 49ers vs Titans
San Francisco 49ers	Measure	Tennessee Titans
58	Plays	58
64%	Pass rate	59%
8.3	Yds / dropback	5.5
4.0	Yds / carry	3.8
3/8	Third downs	9/16

Top targets
SF Samuel 31% · Aiyuk 14% · Jennings 14%
TEN Brown 53% · Swaim 10% · Westbrook-Ikhine 10%

Possession Results

How each possession ended, 49ers vs Titans
Result	SF	TEN
Touchdowns	2	2
Field goals	1	2
Punts	2	5
Turnovers	2	0
Turnovers on downs	1	0

TEN turnover edge: +2

The 49ers opened the scoring on their first possession, a 9-play, 75-yard drive that ended in a touchdown.
The Titans drained the clock with two second-half drives of four to seven minutes.

All 19 possessions, drive by drive

Drive chart
Team	Start	Plays	Yards	Time	Result
SF	Q1 15:00	9	75	5:03	Touchdown
TEN	Q1 9:57	6	8	4:16	Punt
SF	Q1 5:41	8	72	4:10	Interception
TEN	Q1 1:31	3	4	1:41	Punt
SF	Q2 14:50	11	33	6:19	Field goal
TEN	Q2 8:31	6	19	3:54	Punt
SF	Q2 4:37	3	-7	1:30	Punt
TEN	Q2 3:07	6	2	1:47	Punt
SF	Q2 1:20	4	23	1:20	End of half
TEN	Q3 15:00	13	55	6:15	Field goal
SF	Q3 8:45	1	0	0:09	Interception
TEN	Q3 8:36	4	18	1:23	Touchdown
SF	Q3 7:13	8	35	5:20	Downs
TEN	Q3 1:53	7	59	3:51	Touchdown
SF	Q4 13:02	6	32	3:38	Punt
TEN	Q4 9:24	7	33	4:06	Punt
SF	Q4 5:18	8	95	2:58	Touchdown
TEN	Q4 2:20	8	49	2:16	Field goal
SF	Q4 0:04	1	8	0:04	End of game

About these numbers

Possessions that ended with the clock running out at the half or the end of the game aren't counted.

Personnel groupings, average depth of target and pass rate over expected appear when the tracking feed is connected.

49ers vs Titans Head-to-Head

The 49ers and Titans first met in 1970 and have played 16 times since.

All-time series: 10–649ers lead, 16 meetings since 1970
Postseason: 0No playoff meetings
Largest 49ers win: 28–61981
Largest Titans win: 27–131975

Since 2021

1–1 Series tied

2 meetings since the 2021 season, regular season and playoffs.

Oldest to newest. 4 = 49ers win, T = Titans win, outlined = this game.

Recent Meetings

2025 Wk 15 Titans at 49ers, 2025 Wk 15 recap Sun, Dec 14, 2025 SF 37 TEN 24 SF W
2021 Wk 16 49ers at Titans Thu, Dec 23, 2021 TEN 20 SF 17 TEN W

Season to Date (Through Week 18)

The 2021 regular season, from each game's box score.

Season to date, 49ers vs Titans
49ers	Stat	Titans
10-7	Record	12-5

25.1	Points per game	24.6

375.7	Yards per game	342.5

6.1	Yards per play	5.1

21.5	Points allowed per game	20.8

310.0	Yards allowed per game	329.8

49ers vs Titans Odds and Results

How this game finished against the betting lines.

Spread: SF −3.549ers failed to cover by 6.5
Total: 45.5Under: 37 points scored (by 8.5)

Expected vs Actual Scoring

Implied team totals against the actual score
Team	Implied	Actual	Difference
49ers	24.5	17	−7.5
Titans	21.0	20	−1.0

Both offenses finished under the market's expectation, which matches the low fantasy output in the Fantasy tab.

Betting Trends

Each team's 2021 season through this game. Over/under is overs first.

San Francisco 49ers

Against the spread: 7–8
Over/under: 7–7–1
ATS as favorite: 6–7
ATS as underdog: 1–1
ATS on the road: 4–4

Tennessee Titans

Against the spread: 9–6
Over/under: 7–8
ATS as favorite: 3–4
ATS as underdog: 6–2
ATS at home: 5–3

Lines: ESPN's consensus, captured at kickoff. Individual sportsbooks varied.

21+. Gambling problem? Call 1-800-GAMBLER. Betting availability depends on your state.

49ers and Titans in Fantasy

The two teams don't meet again this season. If you roster a 49er or a Titan, these answer the week-to-week question.

Keep Exploring

2021 Game Logs for Players in This Game

49ers vs Titans Game FAQ

Who won the 2021 49ers vs Titans Week 16 game?

The Tennessee Titans beat the San Francisco 49ers 20–17 in Week 16 of the 2021 season. The game was played at Nissan Stadium in Nashville, TN, on December 23, 2021. See the Titans' 2021 schedule.

What was the final score of 49ers vs Titans?

The final score was Titans 20, 49ers 17. The 49ers led 10–0 at halftime, and the second half went 49ers 7, Titans 20.

What happened in the 49ers vs Titans game?

Tennessee erased a 10–0 halftime deficit, outscoring San Francisco 20–7 after the break to win 20–17. San Francisco outgained the Titans 389–278. A.J. Brown led all players with 11 catches for 145 yards and a touchdown. The 49ers committed 2 turnovers, the Titans none.

What was the game-winning score in 49ers vs Titans?

Randy Bullock's 44-yard field goal with 0:04 left in the fourth quarter gave the Titans a 20–17 lead they never gave up. It was the final score of the game.

Who scored the most fantasy points in 49ers vs Titans?

A.J. Brown led the game with 31.5 PPR fantasy points, the WR3 of Week 16, on 11 catches for 145 yards and a touchdown. Deebo Samuel was next with 26.1 (WR5). See A.J. Brown's 2021 game log.

Who led 49ers vs Titans in passing, rushing and receiving?

Jimmy Garoppolo (SF) led all passers with 26 of 35 for 322 yards, a touchdown and 2 interceptions. Jeff Wilson (SF) led in rushing with 14 carries for 45 yards and a touchdown. Deebo Samuel (SF) led in receiving with 9 catches for 159 yards.

How many fantasy points did A.J. Brown score against the 49ers?

A.J. Brown scored 31.5 points in PPR leagues, 26.0 in half-PPR and 20.5 in standard scoring against the 49ers in Week 16 of the 2021 season, on 11 catches for 145 yards and a touchdown. He drew 53% of his team's targets.

Who outperformed and underperformed expected fantasy points in 49ers vs Titans?

Deebo Samuel Sr. outperformed his expected fantasy points the most, scoring 28.1 PPR points on 21.7 xFP (+6.4). Jauan Jennings fell furthest short, with 3.9 points on 8.4 xFP (−4.5). A gap either way reflects efficiency and touchdowns in one game; it is not a forecast. For matchups ahead, see fantasy points allowed by position.

How did the Titans come back to beat the 49ers?

The Titans' chances of winning fell as low as 9% in the third quarter. Randy Bullock's 44-yard field goal then put them ahead for good.

Which team won the turnover battle in 49ers vs Titans?

The Titans won the turnover battle 2–0: the 49ers gave the ball away 2 times and the Titans not at all. The Titans won the game.

What is the all-time 49ers vs Titans record?

The 49ers lead the all-time series 10–6 across 16 meetings since 1970.

When did the 49ers and Titans last play before this game?

Before Week 16 of 2021, they last met in the 2017 season on December 17, 2017, when the 49ers beat the Titans 25–23.

What was the closing spread for 49ers vs Titans?

The consensus closing spread at kickoff was 49ers −3.5, making the San Francisco 49ers 3.5-point favorites, with a closing total of 45.5. That implied about 24.5 points for the 49ers and 21.0 for the Titans.

Did 49ers vs Titans go over or under the total?

The game went under. The consensus closing total was 45.5, and the teams combined for 37 points, 8.5 under the number.

Who covered the spread in 49ers vs Titans?

The Titans covered as 3.5-point underdogs against the closing line of 49ers −3.5. The final margin was 3 points.