Final2021 Week 10

Levi's Stadium, Santa Clara, CA

Los Angeles Rams vs San Francisco 49ers, Week 10 2021

Los Angeles Rams

Away

10

San Francisco 49ers

HomeWon

31

Scoring by quarter
TeamQ1Q2Q3Q4Final
Rams070310
49ers1473731

LAR 10SF 31 Final

  • Passing leader

    Matthew Stafford

    LAR · QB

    11.8PPR pts

    26/41, 243 YDS, 1 TD, 2 INT

  • Top fantasy scorer

    Deebo Samuel Sr.

    SF · WR

    30.3PPR pts

    5 REC, 97 YDS, 1 TD, 1 RUSH TD

  • Rams leader

    Cooper Kupp

    LAR · WR

    23.2PPR pts

    11 REC, 122 YDS

  • Defensive playmaker

    Jimmie Ward

    SF

    2 INT, 1 TD, 2 TKL

49ers 31, Rams 10: San Francisco leads from start to finish

San Francisco led 21–7 at halftime and outscored Los Angeles 10–3 after the break to win 31–10. The 49ers finished with a 335–278 edge in total offense and averaged 5.2 yards per play.

The gap showed up everywhere. The Rams went 3-for-10 on third down and committed two turnovers, while the 49ers kept the ball for 39:03 and finished without a giveaway.

The two teams meet again in Week 14 of 2026. If you roster anyone from either side, run the start/sit call in Redraft Command and it will weigh your lineup, your opponent and your league scoring, not only the player rankings.

Key advantages

  • +0.1 yards/play SF 5.2 · LAR 5.1
  • +2 turnover margin SF 0 turnovers
  • +57 total yards SF 335 · LAR 278

Game Highlights

Official NFL highlights · Opens from YouTube

Got a Ram or 49er on your fantasy team?

Check their next matchup with the Start/Sit Tool, compare their value in the Fantasy Trade Calculator, or connect your league for personalized advice in Redraft Command.

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Why the 49ers Won

San Francisco won the efficiency, turnover, third-down, and time of possession battles.

Team stats comparison, Rams vs 49ers
RamsStat49ers
5.1Yards per play5.2
2Turnovers0
278Total yards335
Other team stats
54Plays64
30%Third-down conversion57%
20:57Time of possession39:03

Scoring Summary

The 49ers scored four touchdowns and one field goal; the Rams scored one touchdown and one field goal.

Scoring plays, Rams vs 49ers
TimeTeamPlayLARSF
1st quarter
1:54SFJimmy Garoppolo → George Kittle, 8-yard TD Takes leadRobbie Gould XP07
0:49SFJimmie Ward 27-yard interception return TD Extends leadRobbie Gould XP014
2nd quarter
13:16LARMatthew Stafford → Tyler Higbee, 10-yard TDMatt Gay XP714
5:24SFDeebo Samuel 8-yard TD run Extends leadRobbie Gould XP721
3rd quarter
4:38SFRobbie Gould 50-yard FG Extends lead724
4th quarter
11:07SFJimmy Garoppolo → Deebo Samuel, 40-yard TD Extends leadRobbie Gould XP731
3:48LARMatt Gay 37-yard FG1031

Fantasy Points: Rams vs 49ers, Week 10 2021

Fantasy leaders

  1. Deebo SamuelSFWR30.3 PTSWR1
  2. Cooper KuppLARWR23.2 PTSWR6
  3. George KittleSFTE16.0 PTSTE5
  4. Jimmy GaroppoloSFQB15.4 PTSQB12

Player Stats

Quarterbacks

Quarterback statistics
PlayerFPTSFINCMP/ATTPass YDSTDINTRush ATTRush YDSRush TDRateStart/Sit
Matthew StaffordLARQB11.8QB1626/412431211067.4Start/Sit →
Jimmy GaroppoloSFQB15.4QB1215/1918220210141.7

WRs, RBs, & TEs

Receiver, running back and tight end statistics
PlayerFPTSFINPOSRush ATTRush YDSRush TDTGTRECRec YDSRec TDStart/Sit
Deebo SamuelSFWR30.3WR1WR536155971
Cooper KuppLARWR23.2WR6WR———13111220Start/Sit →
George KittleSFTE16.0TE5TE———75501Start/Sit →
Tyler HigbeeLARTE11.0TE9TE———53201Start/Sit →
Elijah MitchellSFRB9.1RB28RB27910————
Van JeffersonLARWR8.4WR44WR———73540
Darrell HendersonLARRB8.1RB37RB531064100
Brandon AiyukSFWR5.6WR53WR———43260
Sony MichelLARRB5.1RB46RB420022110
Odell BeckhamLARWR3.8WR70WR———32180
Jeff WilsonSFRB2.8RB53RB10280————
Ben SkowronekLARWR1.8WR90WR———5180Start/Sit →
Jauan JenningsSFWR1.3WR97WR———2130Start/Sit →
Kendall BlantonLARTE1.2TE49TE———1120

Fantasy Usage

Los Angeles Rams

Snap Share

  1. Cooper KuppWR55 snaps100%
  2. Tyler HigbeeTE54 snaps98%
  3. Van JeffersonWR52 snaps95%
  4. Ben SkowronekWR42 snaps76%
  5. Darrell HendersonRB41 snaps75%

Target Share42 targets

  1. Cooper Kupp31%, 13 targets
  2. Van Jefferson17%, 7 targets
  3. Darrell Henderson14%, 6 targets
  4. Tyler Higbee12%, 5 targets
  5. Ben Skowronek12%, 5 targets
  6. Other14%, 6 targets

Carry Share10 carries

  1. Darrell Henderson50%, 5 carries
  2. Sony Michel40%, 4 carries
  3. Matthew Stafford10%, 1 carries

San Francisco 49ers

Snap Share

  1. Brandon AiyukWR61 snaps90%
  2. George KittleTE52 snaps76%
  3. Deebo SamuelWR49 snaps72%
  4. Elijah MitchellRB36 snaps53%
  5. Jauan JenningsWR32 snaps47%

Target Share18 targets

  1. George Kittle39%, 7 targets
  2. Deebo Samuel28%, 5 targets
  3. Brandon Aiyuk22%, 4 targets
  4. Jauan Jennings11%, 2 targets

Carry Share44 carries

  1. Elijah Mitchell61%, 27 carries
  2. Jeff Wilson23%, 10 carries
  3. Deebo Samuel11%, 5 carries
  4. Jimmy Garoppolo5%, 2 carries
View full usage tableHide full usage table
Offensive snaps and share for the skill positions
PlayerSNAPSSNAP %TGTTGT %CAR
Cooper KuppLARWR55100%1331%0
Tyler HigbeeLARTE5498%512%0
Van JeffersonLARWR5295%717%0
Brandon AiyukSFWR6190%422%0
George KittleSFTE5276%739%0
Ben SkowronekLARWR4276%512%0
Darrell HendersonLARRB4175%614%5
Deebo SamuelSFWR4972%528%5
Elijah MitchellSFRB3653%00%27
Jauan JenningsSFWR3247%211%0
Jeff WilsonSFRB2232%00%10
Odell BeckhamLARWR1527%37%0
Trent SherfieldSFWR1826%00%0
Charlie WoernerSFTE1826%00%0
Sony MichelLARRB1425%25%4
Ross DwelleySFTE913%00%0
Travis BenjaminSFWR34%00%0
Kendall BlantonLARTE24%12%0

Fantasy Points vs Expected

Expected points (xFP) are what a player's pass attempts, carries and targets are worth at the league's average rates; the difference is what the player made of them.

  • Biggest overperformer+18.7Deebo Samuel Sr.30.3 PTS vs 11.6 xFP
  • Biggest underperformer−8.2Elijah Mitchell9.1 PTS vs 17.3 xFP
  • Highest expected volume21.9 xFPCooper Kupp23.2 PTS scored
Usage and expected fantasy points
PlayerPTSxFPvs xFPSnap%UsageRte%Pass attCarCar%TgtTgt%
Cooper KuppLAR · WR23.221.9+1.3100%31% tgt—000%1331%
Matthew StaffordLAR · QB11.818.7−6.9100%41 att—41110%00%
Elijah MitchellSF · RB9.117.3−8.253%61% car—02761%00%
Darrell Henderson Jr.LAR · RB8.113.3−5.275%50% car—0550%614%
George KittleSF · TE16.011.8+4.276%37% tgt—000%737%
Van JeffersonLAR · WR8.411.8−3.495%17% tgt—000%717%
Deebo Samuel Sr.SF · WR30.311.6+18.772%26% tgt—0511%526%
Jimmy GaroppoloSF · QB15.49.6+5.8100%19 att—1925%00%
Ben SkowronekLAR · WR1.88.4−6.676%12% tgt—000%512%
Tyler HigbeeLAR · TE11.08.4+2.698%12% tgt—000%512%
Brandon AiyukSF · WR5.66.7−1.190%21% tgt—000%421%
Jeff Wilson Jr.SF · RB2.86.4−3.632%23% car—01023%00%
Sony MichelLAR · RB5.15.9−0.825%40% car—0440%25%
Odell Beckham Jr.LAR · WR3.85.1−1.327%7% tgt—000%37%
Jauan JenningsSF · WR1.33.4−2.147%11% tgt—000%211%
Kendall BlantonLAR · TE1.21.7−0.54%2% tgt—000%12%
Kyle JuszczykSF · RB1.61.7−0.1—5% tgt—000%15%

Team totals: Rams 42 targets and 10 carries; 49ers 19 targets and 44 carries. Shares are from the box score. Snap counts are from the weekly player logs (Sleeper), and include plays wiped out by penalties. Route counts, air yards and red-zone touches appear when the tracking feed is connected. League-average rates from the 2021 season: 1.68 PPR points per target (67% catch rate), 0.64 per carry and 0.44 per pass attempt. They don't adjust for field position or target depth.

Fantasy Verdicts

Matthew Stafford Unlucky

LAR · QB · 11.8 pts on 18.7 expected

26 of 41 passing for 243 yards, 1 touchdown, 2 interceptions; 1 carry for 1 yard.

Verdict: The role was there, worth 18.7 points at league-average rates; the production wasn't.

Start/Sit: Matthew Stafford →

Jimmy Garoppolo Ran hot

SF · QB · 15.4 pts on 9.6 expected

15 of 19 passing for 182 yards, 2 touchdowns; 2 carries for 1 yard.

Verdict: The opportunities were worth 9.6 points; the touchdowns supplied the rest, and they are the part least likely to repeat.

Cooper Kupp Strong role

LAR · WR · 23.2 pts on 21.9 expected

13 targets (31% of the team's), 11 catches for 122 yards.

Verdict: The points matched the role, 21.9 expected.

Start/Sit: Cooper Kupp →

Darrell Henderson Jr. Unlucky

LAR · RB · 8.1 pts on 13.3 expected

6 targets (14% of the team's), 4 catches for 10 yards; 5 carries (50% of the team's) for 31 yards.

Verdict: The role was there, worth 13.3 points at league-average rates; the production wasn't.

Elijah Mitchell Volume, no payoff

SF · RB · 9.1 pts on 17.3 expected

27 carries (61% of the team's) for 91 yards.

Verdict: The role was there, worth 17.3 points at league-average rates; the production wasn't.

George Kittle Strong role

SF · TE · 16.0 pts on 11.8 expected

7 targets (37% of the team's), 5 catches for 50 yards and 1 touchdown.

Verdict: The points matched the role, 11.8 expected.

Start/Sit: George Kittle →

Deebo Samuel Sr. Ran hot

SF · WR · 30.3 pts on 11.6 expected

5 targets (26% of the team's), 5 catches for 97 yards and 1 touchdown; 5 carries (11% of the team's) for 36 yards and 1 touchdown.

Verdict: The opportunities were worth 11.6 points; the touchdowns supplied the rest, and they are the part least likely to repeat.

Ben Skowronek Unlucky

LAR · WR · 1.8 pts on 8.4 expected

5 targets (12% of the team's), 1 catch for 8 yards.

Verdict: The role was there, worth 8.4 points at league-average rates; the production wasn't.

Start/Sit: Ben Skowronek →

Stock Up, Stock Down

Los Angeles Rams

  • Stock up: Van Jefferson played 95% of the snaps, up from a 78% season average.
  • Stock up: Ben Skowronek played 76% of the snaps, up from a 11% season average.
  • Stock down: Odell Beckham Jr. played 27% of the snaps, down from a 69% season average.

San Francisco 49ers

  • Stock up: Brandon Aiyuk played 90% of the snaps, up from a 72% season average.
  • Stock up: Jauan Jennings played 47% of the snaps, up from a 10% season average.
  • Stock down: George Kittle played 76% of the snaps, down from a 92% season average.

Fantasy Matchups

Fantasy points allowed per game by position, 2021 through Week 18.

Fantasy points allowed per game by position, Rams defense and 49ers defense
Points allowed toRams D49ers D
QBs16.017.7
RBs20.920.9
WRs36.535.4
TEs11.99.1

Regular season, summed from each game's box score and scored with this page's rules.

How the Game Swung

San Francisco opened at 40% win probability and passed 98% in the third quarter on the way to the win.

49ers win probability

49ers win probability by game minute49ers started at 40%, stood at 90% at halftime and finished at 100%, across 7 scoring plays.Q1Q2Q3Q4100%50%0%

Key Swings

  1. +23Garoppolo → Kittle, 8-yd TD41% → 64%Q1 1:54
  2. +19Ward 27-yd pick-six64% → 83%Q1 0:49
  3. −19Stafford → Higbee, 10-yd TD84% → 65%Q2 13:16
  4. +19Samuel 8-yd TD run68% → 88%Q2 5:24
  5. +3Gould 50-yd FG95% → 98%Q3 4:38

Swing in 49ers win probability, in points

Play Calling and Possessions

Play calling, Rams vs 49ers
Los Angeles RamsMeasureSan Francisco 49ers
54Plays64
81%Pass rate31%
5.1Yds / dropback8.9
5.2Yds / carry3.5
3/10Third downs8/14

Efficiency edge San Francisco ran 10 more plays and gained 3.9 more yards per dropback.

  • Top targets
  • LAR Kupp 31% · Jefferson 17% · Henderson 14%
  • SF Kittle 37% · Samuel 26% · Aiyuk 21%

Possession Results

How each possession ended, Rams vs 49ers
ResultLARSF
Touchdowns13
Field goals11
Punts33
Turnovers20
Turnovers on downs21

SF turnover edge: +2

  • The 49ers opened the scoring on their first possession, a 18-play, 93-yard drive that ended in a touchdown.
  • The 49ers scored touchdowns on two of their first three drives.
All 19 possessions, drive by drive
Drive chart
TeamStartPlaysYardsTimeResult
LARQ1 15:004172:03Interception
SFQ1 12:57189311:03Touchdown
LARQ1 1:544-11:05Interception
LARQ1 0:497752:33Touchdown
SFQ2 13:1611917:52Touchdown
LARQ2 5:249645:12Downs
SFQ2 0:121-10:12End of half
SFQ3 15:004162:35Punt
LARQ3 12:25351:33Punt
SFQ3 10:5210316:14Field goal
LARQ3 4:38360:56Punt
SFQ3 3:426182:49Punt
LARQ3 0:53330:53Punt
SFQ4 15:006563:53Touchdown
LARQ4 11:0714685:07Downs
SFQ4 6:00311:01Punt
LARQ4 4:597331:11Field goal
SFQ4 3:486203:24Downs
LARQ4 0:24170:24End of game
About these numbers

The 49ers' interception touchdown is counted as a Rams interception, not as a 49ers possession. Possessions that ended with the clock running out at the half or the end of the game aren't counted.

Personnel groupings, average depth of target and pass rate over expected appear when the tracking feed is connected.

Rams vs 49ers Head-to-Head

The Rams and 49ers first met in 1950 and have played 155 times since. They have been NFC West rivals since 1970.

All-time series
80–72–349ers lead, 155 meetings since 1950
Postseason
1–1Rams won in 2021; 49ers won in 1989
Largest Rams win
56–71958
Largest 49ers win
48–01987

Since 2021

7–5 49ers lead

12 meetings since the 2021 season, regular season and playoffs.

Oldest to newest. 4 = 49ers win, R = Rams win, outlined = this game.

2026 Meetings

  • Week 14 Rams at 49ers Upcoming

Recent Meetings

Season to Date (Through Week 18)

The 2021 regular season, from each game's box score.

Season to date, Rams vs 49ers
RamsStat49ers
12-5Record10-7
27.1Points per game25.1
372.1Yards per game375.7
6.0Yards per play6.1
21.9Points allowed per game21.5
344.9Yards allowed per game310.0

Rams vs 49ers Odds and Results

How this game finished against the betting lines.

Spread
LAR −3.5Rams failed to cover by 24.5
Total
50Under: 41 points scored (by 9)

Expected vs Actual Scoring

Implied team totals against the actual score
TeamImpliedActualDifference
Rams26.810−16.8
49ers23.331+7.8

The 49ers beat their implied total and the Rams fell short of theirs; the Fantasy tab has the player lines behind it.

Betting Trends

Each team's 2021 season through this game. Over/under is overs first.

Los Angeles Rams

Against the spread
4–6
Over/under
5–4–1
ATS as favorite
3–6
ATS as underdog
1–0
ATS on the road
2–3

San Francisco 49ers

Against the spread
3–6
Over/under
5–4
ATS as favorite
2–5
ATS as underdog
1–1
ATS at home
1–4

Lines: ESPN's consensus, captured at kickoff. Individual sportsbooks varied.

21+. Gambling problem? Call 1-800-GAMBLER. Betting availability depends on your state.

Rams vs 49ers Fantasy Outlook for 2026

One meeting is left on the 2026 schedule: Week 14 in San Francisco. Here's how to decide who to play in your league.

Keep Exploring

2021 Game Logs for Players in This Game

Rams vs 49ers Game FAQ

Who won the 2021 Rams vs 49ers Week 10 game?

The San Francisco 49ers beat the Los Angeles Rams 31–10 in Week 10 of the 2021 season. The game was played at Levi's Stadium in Santa Clara, CA, on November 15, 2021. See the 49ers' 2021 schedule.

What was the final score of Rams vs 49ers?

The final score was 49ers 31, Rams 10. The 49ers led 21–7 at halftime, and the second half went Rams 3, 49ers 10.

What happened in the Rams vs 49ers game?

San Francisco led 21–7 at halftime and outscored Los Angeles 10–3 after the break to win 31–10. The 49ers finished with a 335–278 edge in total offense and averaged 5.2 yards per play. Deebo Samuel led all players with 5 catches for 97 yards and a touchdown, plus 5 carries for 36 rushing yards and a touchdown. The Rams committed 2 turnovers, the 49ers none.

Who scored the most fantasy points in Rams vs 49ers?

Deebo Samuel led the game with 30.3 PPR fantasy points, the WR1 of Week 10, on 5 catches for 97 yards and a touchdown, plus 5 carries for 36 rushing yards and a touchdown. Cooper Kupp was next with 23.2 (WR6). See Deebo Samuel's 2021 game log.

Who led Rams vs 49ers in passing, rushing and receiving?

Matthew Stafford (LAR) led all passers with 26 of 41 for 243 yards, a touchdown and 2 interceptions. Elijah Mitchell (SF) led in rushing with 27 carries for 91 yards. Cooper Kupp (LAR) led in receiving with 11 catches for 122 yards.

How many fantasy points did Deebo Samuel score against the Rams?

Deebo Samuel scored 30.3 points in PPR leagues, 27.8 in half-PPR and 25.3 in standard scoring against the Rams in Week 10 of the 2021 season, on 5 catches for 97 yards and a touchdown, plus 5 carries for 36 rushing yards and a touchdown.

Who outperformed and underperformed expected fantasy points in Rams vs 49ers?

Deebo Samuel Sr. outperformed his expected fantasy points the most, scoring 30.3 PPR points on 11.6 xFP (+18.7). Elijah Mitchell fell furthest short, with 9.1 points on 17.3 xFP (−8.2). A gap either way reflects efficiency and touchdowns in one game; it is not a forecast. For matchups ahead, see fantasy points allowed by position.

How did the 49ers beat the Rams?

The 49ers beat the Rams 31–10 because they averaged 5.2 yards per play to 5.1, won the turnover battle 2–0, and outgained them 335–278.

Which team won the turnover battle in Rams vs 49ers?

The 49ers won the turnover battle 2–0: the Rams gave the ball away 2 times and the 49ers not at all. The 49ers won the game.

What is the all-time Rams vs 49ers record?

The 49ers lead the all-time series 80–72–3 across 155 meetings since 1950, including a 1–1 record in the postseason.

When did the Rams and 49ers last play before this game?

Before Week 10 of 2021, they last met in the 2020 season on November 29, 2020, when the 49ers beat the Rams 23–20.

Have the Rams and 49ers met in the playoffs?

Yes, 2 times, most recently in the 2021 playoffs. The Rams are 1–1 against the 49ers in the postseason.

What was the closing spread for Rams vs 49ers?

The consensus closing spread at kickoff was Rams −3.5, making the Los Angeles Rams 3.5-point favorites, with a closing total of 50. That implied about 26.8 points for the Rams and 23.3 for the 49ers.

Did Rams vs 49ers go over or under the total?

The game went under. The consensus closing total was 50, and the teams combined for 41 points, 9 under the number.

Who covered the spread in Rams vs 49ers?

The 49ers covered as 3.5-point underdogs against the closing line of Rams −3.5. The final margin was 21 points.