Final2022 Week 11

Estadio Azteca, Mexico City

San Francisco 49ers vs Arizona Cardinals, Week 11 2022

San Francisco 49ers

Won

38

Arizona Cardinals

10

Scoring by quarter
TeamQ1Q2Q3Q4Final
49ers01714738
Cardinals370010

SF 38ARI 10 Final

  • Passing leader

    Jimmy Garoppolo

    SF · QB

    25.4PPR pts

    20/29, 228 YDS, 4 TD

  • Top fantasy scorer

    George Kittle

    SF · TE

    24.4PPR pts

    4 REC, 84 YDS, 2 TD

  • Cardinals leader

    Greg Dortch

    ARI · WR

    19.3PPR pts

    9 REC, 103 YDS

  • Defensive playmaker

    Jimmie Ward

    SF

    1 INT, 5 TKL

49ers 38, Cardinals 10: San Francisco pulls away from Arizona

San Francisco led 17–10 at halftime after a 17-point second quarter and outscored Arizona 21–0 after the break to win 38–10. The 49ers finished with a 387–314 edge in total offense and averaged 6.8 yards per play.

The gap showed up everywhere. The Cardinals went 8-for-16 on third down and committed two turnovers, while the 49ers finished without a giveaway.

The two teams meet again in Week 18 of 2026. If you roster anyone from either side, run the start/sit call in Redraft Command and it will weigh your lineup, your opponent and your league scoring, not only the player rankings.

Key advantages

  • +2.4 yards/play SF 6.8 · ARI 4.4
  • +2 turnover margin SF 0 turnovers
  • +73 total yards SF 387 · ARI 314

Game Highlights

Official NFL highlights · Opens from YouTube

Got a 49er or Cardinal on your fantasy team?

Check their next matchup with the Start/Sit Tool, compare their value in the Fantasy Trade Calculator, or connect your league for personalized advice in Redraft Command.

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Why the 49ers Won

San Francisco won the efficiency, turnover, and third-down battles.

Team stats comparison, 49ers vs Cardinals
49ersStatCardinals
6.8Yards per play4.4
0Turnovers2
387Total yards314
Other team stats
57Plays71
55%Third-down conversion50%
29:09Time of possession30:51

Scoring Summary

The 49ers scored five touchdowns and one field goal; the Cardinals scored one touchdown and one field goal.

Scoring plays, 49ers vs Cardinals
TimeTeamPlaySFARI
1st quarter
8:00ARIMatt Prater 40-yard FG Takes lead03
2nd quarter
13:35SFJimmy Garoppolo → Brandon Aiyuk, 7-yard TD Takes leadRobbie Gould XP73
8:42SFJimmy Garoppolo → George Kittle, 39-yard TD Extends leadRobbie Gould XP143
4:19ARIJames Conner 2-yard TD runMatt Prater XP1410
0:43SFRobbie Gould 39-yard FG Extends lead1710
3rd quarter
10:34SFDeebo Samuel 39-yard TD run Extends leadRobbie Gould XP2410
0:28SFJimmy Garoppolo → Brandon Aiyuk, 13-yard TD Extends leadRobbie Gould XP3110
4th quarter
10:08SFJimmy Garoppolo → George Kittle, 32-yard TD Extends leadRobbie Gould XP3810

Fantasy Points: 49ers vs Cardinals, Week 11 2022

Fantasy leaders

  1. Jimmy GaroppoloSFQB25.4 PTSQB5
  2. George KittleSFTE24.4 PTSTE2
  3. Deebo SamuelSFWR22.4 PTSWR5
  4. Greg DortchARIWR19.3 PTSWR10

Player Stats

Quarterbacks

Quarterback statistics
PlayerFPTSFINCMP/ATTPass YDSTDINTRush ATTRush YDSRush TDRateStart/Sit
Jimmy GaroppoloSFQB25.4QB520/2922840130131.9
Colt McCoyARIQB8.3QB2324/342180136075.4
Trace McSorleyARIQB2.0QB316/10590116037.1
Brock PurdySFQB0.3QB33————330—Start/Sit →

WRs, RBs, & TEs

Receiver, running back and tight end statistics
PlayerFPTSFINPOSRush ATTRush YDSRush TDTGTRECRec YDSRec TDStart/Sit
George KittleSFTE24.4TE2TE———64842Start/Sit →
Deebo SamuelSFWR22.4WR5WR337197570
Greg DortchARIWR19.3WR10WR———1091030Start/Sit →
DeAndre HopkinsARIWR18.1WR12WR———129910
Christian McCaffreySFRB17.6RB11RB739077670Start/Sit →
Brandon AiyukSFWR16.0WR15WR———42202
James ConnerARIRB13.4RB16RB1442152120
A.J. GreenARIWR10.0WR38WR———95500
Elijah MitchellSFRB5.9RB36RB9590————
Trey McBrideARITE5.4TE19TE———44140Start/Sit →
Keaontay IngramARIRB1.9RB52RB5190————
Maxx WilliamsARITE1.7TE41TE———1170
Jordan MasonSFRB1.4RB61RB4140————
Jauan JenningsSFWR0.0—WR———2000Start/Sit →
Stephen AndersonARITE0.0—TE———1000
Ray-Ray McCloudSFWR0.0—WR———1000
Rondale MooreARIWR-0.6—WR1-60————

Fantasy Usage

San Francisco 49ers

Snap Share

  1. Brandon AiyukWR46 snaps79%
  2. George KittleTE43 snaps74%
  3. Christian McCaffreyRB38 snaps66%
  4. Deebo SamuelWR34 snaps59%
  5. Tyler KroftTE27 snaps47%

Target Share29 targets

  1. Deebo Samuel31%, 9 targets
  2. Christian McCaffrey24%, 7 targets
  3. George Kittle21%, 6 targets
  4. Brandon Aiyuk14%, 4 targets
  5. Jauan Jennings7%, 2 targets
  6. Other3%, 1 targets

Carry Share27 carries

  1. Elijah Mitchell33%, 9 carries
  2. Christian McCaffrey26%, 7 carries
  3. Jordan Mason15%, 4 carries
  4. Deebo Samuel11%, 3 carries
  5. Brock Purdy11%, 3 carries
  6. Other4%, 1 carries

Arizona Cardinals

Snap Share

  1. Greg DortchWR66 snaps93%
  2. A.J. GreenWR55 snaps77%
  3. James ConnerRB55 snaps77%
  4. Trey McBrideTE54 snaps76%
  5. DeAndre HopkinsWR49 snaps69%

Target Share42 targets

  1. DeAndre Hopkins29%, 12 targets
  2. Greg Dortch24%, 10 targets
  3. A.J. Green21%, 9 targets
  4. James Conner12%, 5 targets
  5. Trey McBride10%, 4 targets
  6. Other5%, 2 targets

Carry Share24 carries

  1. James Conner58%, 14 carries
  2. Keaontay Ingram21%, 5 carries
  3. Colt McCoy13%, 3 carries
  4. Trace McSorley4%, 1 carries
  5. Rondale Moore4%, 1 carries
View full usage tableHide full usage table
Offensive snaps and share for the skill positions
PlayerSNAPSSNAP %TGTTGT %CAR
Greg DortchARIWR6693%1024%0
Brandon AiyukSFWR4679%414%0
A.J. GreenARIWR5577%921%0
James ConnerARIRB5577%512%14
Trey McBrideARITE5476%410%0
George KittleSFTE4374%621%0
DeAndre HopkinsARIWR4969%1229%0
Christian McCaffreySFRB3866%724%7
Deebo SamuelSFWR3459%931%3
Tyler KroftSFTE2747%00%0
Robbie ChosenARIWR3346%00%0
Jauan JenningsSFWR2238%27%0
Keaontay IngramARIRB1825%00%5
Elijah MitchellSFRB1322%00%9
Charlie WoernerSFTE1119%00%0
Maxx WilliamsARITE1318%12%0
Danny GraySFWR1017%00%0
Stephen AndersonARITE1014%12%0
Ray-Ray McCloudSFWR814%13%0
Jordan MasonSFRB712%00%4
Ross DwelleySFTE47%00%0
Rondale MooreARIWR23%00%1

Fantasy Points vs Expected

Expected points (xFP) are what a player's pass attempts, carries and targets are worth at the league's average rates; the difference is what the player made of them.

  • Biggest overperformer+14.4George Kittle24.4 PTS vs 10.0 xFP
  • Biggest underperformer−8.0Colt McCoy8.3 PTS vs 16.3 xFP
  • Highest expected volume20.0 xFPDeAndre Hopkins18.1 PTS scored
Usage and expected fantasy points
PlayerPTSxFPvs xFPSnap%UsageRte%Pass attCarCar%TgtTgt%
DeAndre HopkinsARI · WR18.120.0−1.969%29% tgt—000%1229%
James ConnerARI · RB13.417.3−3.977%58% car—01458%512%
Deebo Samuel Sr.SF · WR22.416.9+5.559%31% tgt—0311%931%
Greg DortchARI · WR19.316.7+2.693%24% tgt—000%1024%
Colt McCoyARI · QB8.316.3−8.079%34 att—34313%00%
Christian McCaffreySF · RB17.616.2+1.466%25% car—0725%724%
A.J. GreenARI · WR10.015.0−5.077%21% tgt—000%921%
Jimmy GaroppoloSF · QB25.412.9+12.588%29 att—2914%00%
George KittleSF · TE24.410.0+14.474%21% tgt—000%621%
Brandon AiyukSF · WR16.06.7+9.379%14% tgt—000%414%
Trey McBrideARI · TE5.46.7−1.376%10% tgt—000%410%
Elijah MitchellSF · RB5.95.8+0.122%32% car—0932%00%
Trace McSorleyARI · QB2.04.9−2.921%10 att—1014%00%
Jauan JenningsSF · WR0.03.3−3.338%7% tgt—000%27%
Keaontay IngramARI · RB1.93.2−1.325%21% car—0521%00%
Jordan MasonSF · RB1.42.6−1.212%14% car—0414%00%
Brock PurdySF · QB0.31.9−1.612%0 att—0311%00%
Maxx WilliamsARI · TE1.71.70.018%2% tgt—000%12%
Ray-Ray McCloud IIISF · WR0.01.7−1.714%3% tgt—000%13%
Stephen AndersonARI · TE0.01.7−1.714%2% tgt—000%12%
Kyle JuszczykSF · RB0.40.6−0.2—4% car—014%00%
Rondale MooreARI · WR-0.60.6−1.23%4% car—014%00%

Team totals: 49ers 29 targets and 28 carries; Cardinals 42 targets and 24 carries. Shares are from the box score. Snap counts are from the weekly player logs (Sleeper), and include plays wiped out by penalties. Route counts, air yards and red-zone touches appear when the tracking feed is connected. League-average rates from the 2022 season: 1.67 PPR points per target (67% catch rate), 0.64 per carry and 0.42 per pass attempt. They don't adjust for field position or target depth.

Fantasy Verdicts

Jimmy Garoppolo Ran hot

SF · QB · 25.4 pts on 12.9 expected

20 of 29 passing for 228 yards, 4 touchdowns; 1 carry for 3 yards.

Verdict: The opportunities were worth 12.9 points; the touchdowns supplied the rest, and they are the part least likely to repeat.

Colt McCoy Unlucky

ARI · QB · 8.3 pts on 16.3 expected

24 of 34 passing for 218 yards, 1 interception; 3 carries for 6 yards.

Verdict: The role was there, worth 16.3 points at league-average rates; the production wasn't.

Deebo Samuel Sr. Ran hot

SF · WR · 22.4 pts on 16.9 expected

9 targets (31% of the team's), 7 catches for 57 yards; 3 carries (11% of the team's) for 37 yards and 1 touchdown.

Verdict: The opportunities were worth 16.9 points; the touchdowns supplied the rest, and they are the part least likely to repeat.

Christian McCaffrey

SF · RB · 17.6 pts on 16.2 expected

7 targets (24% of the team's), 7 catches for 67 yards; 7 carries (25% of the team's) for 39 yards.

Verdict: The points matched the role, 16.2 expected.

Start/Sit: Christian McCaffrey →

DeAndre Hopkins

ARI · WR · 18.1 pts on 20.0 expected

12 targets (29% of the team's), 9 catches for 91 yards.

Verdict: The points matched the role, 20.0 expected.

James Conner

ARI · RB · 13.4 pts on 17.3 expected

5 targets (12% of the team's), 2 catches for 12 yards; 14 carries (58% of the team's) for 42 yards and 1 touchdown.

Verdict: The points matched the role, 17.3 expected.

A.J. Green Unlucky

ARI · WR · 10.0 pts on 15.0 expected

9 targets (21% of the team's), 5 catches for 50 yards.

Verdict: The role was there, worth 15.0 points at league-average rates; the production wasn't.

George Kittle Ran hot

SF · TE · 24.4 pts on 10.0 expected

6 targets (21% of the team's), 4 catches for 84 yards and 2 touchdowns.

Verdict: The opportunities were worth 10.0 points; the touchdowns supplied the rest, and they are the part least likely to repeat.

Start/Sit: George Kittle →

Stock Up, Stock Down

San Francisco 49ers

  • Stock down: Deebo Samuel Sr. played 59% of the snaps, down from a 82% season average.
  • Stock down: George Kittle played 74% of the snaps, down from a 94% season average.

Arizona Cardinals

  • Stock up: James Conner played 77% of the snaps, up from a 60% season average.
  • Stock up: Greg Dortch played 93% of the snaps, up from a 38% season average.
  • Stock up: A.J. Green played 77% of the snaps, up from a 53% season average.

Fantasy Matchups

Fantasy points allowed per game by position, 2022 through Week 18.

Fantasy points allowed per game by position, 49ers defense and Cardinals defense
Points allowed to49ers DCardinals D
QBs14.618.0
RBs15.525.4
WRs36.430.2
TEs10.216.7

Regular season, summed from each game's box score and scored with this page's rules.

How the Game Swung

Arizona opened at 24% win probability and fell below 2% in the third quarter.

Cardinals win probability

Cardinals win probability by game minuteCardinals started at 24%, stood at 11% at halftime and finished at 0%, across 8 scoring plays.Q1Q2Q3Q4100%50%0%

Key Swings

  1. +8Prater 40-yd FG25% → 34%Q1 8:00
  2. −20Garoppolo → Aiyuk, 7-yd TD37% → 17%Q2 13:35
  3. −12Garoppolo → Kittle, 39-yd TD18% → 6%Q2 8:42
  4. +12Conner 2-yd TD run5% → 18%Q2 4:19
  5. −8Samuel 39-yd TD run10% → 2%Q3 10:34

Swing in Cardinals win probability, in points

Play Calling and Possessions

Play calling, 49ers vs Cardinals
San Francisco 49ersMeasureArizona Cardinals
57Plays71
51%Pass rate66%
7.9Yds / dropback5.3
5.7Yds / carry2.8
6/11Third downs8/16

Efficiency edge San Francisco ran 14 fewer plays but gained 2.6 more yards per dropback.

  • Top targets
  • SF Samuel 31% · McCaffrey 24% · Kittle 21%
  • ARI Hopkins 29% · Dortch 24% · Green 21%

Possession Results

How each possession ended, 49ers vs Cardinals
ResultSFARI
Touchdowns51
Field goals11
Punts44
Turnovers02
Turnovers on downs02

SF turnover edge: +2

  • The Cardinals opened the scoring on their second possession, a 11-play, 58-yard drive that ended in a field goal.
All 22 possessions, drive by drive
Drive chart
TeamStartPlaysYardsTimeResult
ARIQ1 15:00301:28Punt
SFQ1 13:32320:54Punt
ARIQ1 12:3811584:38Field goal
SFQ1 8:004172:13Punt
ARIQ1 5:476193:06Punt
SFQ1 2:419824:06Touchdown
ARIQ2 13:358193:58Interception
SFQ2 9:373460:55Touchdown
ARIQ2 8:429754:23Touchdown
SFQ2 4:1910543:36Field goal
ARIQ2 0:433-10:43End of half
SFQ3 15:008754:26Touchdown
ARIQ3 10:348342:42Downs
SFQ3 7:523-31:28Punt
ARIQ3 6:24301:59Punt
SFQ3 4:256473:57Touchdown
ARIQ3 0:286252:18Downs
SFQ4 13:105503:02Touchdown
ARIQ4 10:085282:11Punt
SFQ4 7:57392:25Punt
ARIQ4 5:3210523:25Interception
SFQ4 2:07482:07End of game
About these numbers

Possessions that ended with the clock running out at the half or the end of the game aren't counted.

Personnel groupings, average depth of target and pass rate over expected appear when the tracking feed is connected.

49ers vs Cardinals Head-to-Head

The 49ers and Cardinals first met in 1951 and have played 70 times since. They have been NFC West rivals since 2002.

All-time series
39–3149ers lead, 70 meetings since 1951
Postseason
0No playoff meetings
Largest 49ers win
50–142003
Largest Cardinals win
47–72015

Since 2021

7–4 49ers lead

11 meetings since the 2021 season, regular season and playoffs.

Oldest to newest. 4 = 49ers win, C = Cardinals win, outlined = this game.

2026 Meetings

  • Week 18 49ers at Cardinals Upcoming

Recent Meetings

Season to Date (Through Week 18)

The 2022 regular season, from each game's box score.

Season to date, 49ers vs Cardinals
49ersStatCardinals
13-4Record4-13
26.5Points per game20.0
365.6Yards per game323.5
5.9Yards per play4.8
16.3Points allowed per game26.4
300.6Yards allowed per game348.9

49ers vs Cardinals Odds and Results

How this game finished against the betting lines.

Spread
SF −9.549ers covered by 18.5
Total
43Over: 48 points scored (by 5)

Expected vs Actual Scoring

Implied team totals against the actual score
TeamImpliedActualDifference
49ers26.338+11.8
Cardinals16.810−6.8

The 49ers beat their implied total and the Cardinals fell short of theirs; the Fantasy tab has the player lines behind it.

Betting Trends

Last 3 meetings: Cardinals 2–1 ATS, overs 2–1.

Each team's 2022 season through this game. Over/under is overs first.

San Francisco 49ers

Against the spread
5–5
Over/under
4–6
ATS as favorite
5–4
ATS as underdog
0–1
ATS on the road
3–3

Arizona Cardinals

Against the spread
5–6
Over/under
6–4–1
ATS as favorite
1–2
ATS as underdog
4–4
ATS at home
2–4

Lines: ESPN's consensus, captured at kickoff. Individual sportsbooks varied.

21+. Gambling problem? Call 1-800-GAMBLER. Betting availability depends on your state.

49ers vs Cardinals Fantasy Outlook for 2026

One meeting is left on the 2026 schedule: Week 18 in Arizona. Here's how to decide who to play in your league.

Keep Exploring

2022 Game Logs for Players in This Game

49ers vs Cardinals Game FAQ

Who won the 2022 49ers vs Cardinals Week 11 game?

The San Francisco 49ers beat the Arizona Cardinals 38–10 in Week 11 of the 2022 season. The game was played at Estadio Azteca in Mexico City on November 21, 2022. See the 49ers' 2022 schedule.

What was the final score of 49ers vs Cardinals?

The final score was 49ers 38, Cardinals 10. The 49ers led 17–10 at halftime, and the second half went 49ers 21, Cardinals 0.

What happened in the 49ers vs Cardinals game?

San Francisco led 17–10 at halftime after a 17-point second quarter and outscored Arizona 21–0 after the break to win 38–10. The 49ers finished with a 387–314 edge in total offense and averaged 6.8 yards per play. Jimmy Garoppolo led all players with 20 of 29 passing for 228 yards and 4 touchdowns, plus a carry for 3 rushing yards. The Cardinals committed 2 turnovers, the 49ers none.

Who scored the most fantasy points in 49ers vs Cardinals?

Jimmy Garoppolo led the game with 25.4 PPR fantasy points, the QB5 of Week 11, on 20 of 29 passing for 228 yards and 4 touchdowns, plus a carry for 3 rushing yards. George Kittle was next with 24.4 (TE2).

Who led 49ers vs Cardinals in passing, rushing and receiving?

Jimmy Garoppolo (SF) led all passers with 20 of 29 for 228 yards and 4 touchdowns. Elijah Mitchell (SF) led in rushing with 9 carries for 59 yards. Greg Dortch (ARI) led in receiving with 9 catches for 103 yards.

How many fantasy points did Jimmy Garoppolo score against the Cardinals?

Jimmy Garoppolo scored 25.4 fantasy points against the Cardinals in Week 11 of the 2022 season, the same in PPR, half-PPR and standard scoring because he had no catches, on 20 of 29 passing for 228 yards and 4 touchdowns, plus a carry for 3 rushing yards.

Who outperformed and underperformed expected fantasy points in 49ers vs Cardinals?

George Kittle outperformed his expected fantasy points the most, scoring 24.4 PPR points on 10.0 xFP (+14.4). Colt McCoy fell furthest short, with 8.3 points on 16.3 xFP (−8.0). A gap either way reflects efficiency and touchdowns in one game; it is not a forecast. For matchups ahead, see fantasy points allowed by position.

Who had the highest expected fantasy points in 49ers vs Cardinals?

DeAndre Hopkins had the most fantasy opportunity in the game, worth 20.0 expected PPR points (xFP) at league-average rates, and scored 18.1. Expected points measure the volume of a player's pass attempts, carries and targets, not how well he used them.

How did the 49ers beat the Cardinals?

The 49ers beat the Cardinals 38–10 because they averaged 6.8 yards per play to 4.4, won the turnover battle 2–0, and outgained them 387–314.

Which team won the turnover battle in 49ers vs Cardinals?

The 49ers won the turnover battle 2–0: the Cardinals gave the ball away 2 times and the 49ers not at all. The 49ers won the game.

What is the all-time 49ers vs Cardinals record?

The 49ers lead the all-time series 39–31 across 70 meetings since 1951.

When did the 49ers and Cardinals last play before this game?

Before Week 11 of 2022, they last met in the 2021 season on November 7, 2021, when the Cardinals beat the 49ers 31–17.

What was the closing spread for 49ers vs Cardinals?

The consensus closing spread at kickoff was 49ers −9.5, making the San Francisco 49ers 9.5-point favorites, with a closing total of 43. That implied about 26.3 points for the 49ers and 16.8 for the Cardinals.

Did 49ers vs Cardinals go over or under the total?

The game went over. The consensus closing total was 43, and the teams combined for 48 points, 5 over the number.

Who covered the spread in 49ers vs Cardinals?

The 49ers covered by 18.5 against the closing line of 49ers −9.5. The final margin was 28 points.